Eustachian tube dysfunction in candidates for surgery for obstructive sleep apnoea syndrome

A novel diagnostic tool for chronic obstructive eustachian tube dysfunction—the eustachian tube score.

OBJECTIVES/HYPOTHESIS The purpose of this study was to introduce a new tool for the diagnosis of chronic obstructive eustachian tube dysfunction (ETD) and as a follow-up tool for eustachian tube therapy using objective and subjective elements. STUDY DESIGN Combined, prospective, retrospective clinical study at a tertiary referral center. METHODS Physical examination, history, tympanometry, ...

Obstructive Sleep Apnoea Syndrome

Maxillo-mandibular surgery for obstructive sleep apnoea.

Many therapeutic approaches, including mandibular surgery, have been proposed for the treatment of obstructive sleep apnoea syndrome. In the largest study of its type yet reported, 54 patients (population A) underwent mandibular surgery: 36 had palato-pharyngoplasty and inferior sagittal osteotomy of the mandible with hyoid myotomy and resuspension, and 18 (population B) had maxillo-mandibular ...

Obstructive Sleep Apnoea Syndrome

Clock gene dysfunction in patients with obstructive sleep apnoea syndrome.

Clock genes regulate mammalian circadian rhythms, and dysfunction of clock genes can contribute to various disorders. To investigate whether obstructive sleep apnoea syndrome (OSAS) influences clock gene function, the present authors examined Period1 (Per1) mRNA expression in vitro and in vivo. In eight healthy subjects and eight OSAS patients, plasma noradrenaline, serum interleukin (IL)-6, hi...